Facilities Engineer

Synthego is seeking an experienced and technically driven

Facilities Engineer

to support the operation, maintenance, troubleshooting, and continuous improvement of critical facility infrastructure within a GMP-regulated biotech manufacturing and laboratory environment.

This role is responsible for ensuring the reliability, safety, and regulatory compliance of facility systems, with particular emphasis on GMP HVAC systems, environmental controls, hazardous materials infrastructure, and critical utilities.

The Facilities Engineer will serve as a technical subject matter expert in complex system troubleshooting, root cause investigations, nonconformance management, and engineering problem-solving. The successful candidate will demonstrate strong technical ownership, an understanding of quality management systems, and the ability to develop and implement sustainable corrective actions.

This position requires close collaboration with Manufacturing, Quality Assurance, Environmental Health & Safety (EHS), Service Engineering, and external service providers to ensure that facility infrastructure supports safe, compliant, and uninterrupted operations.

What You'll Do:

Facility Operations and Maintenance

Support 24/7 facility operations and ensure continuity of critical systems and site security

Oversee cleaning services, pest control, waste disposal, and other facility-related vendors

Work alongside property management in facilitating property acquisition, maintenance events, or other services

Maintain building operations to ensure functionality, cleanliness, and organization

Perform daily rounds and record readings of critical systems and equipment

Install and relocate furniture, fixtures, and equipment in partnership with office management

Maintain inventory of spare parts and coordinate procurement as needed

Support and help prioritize facility improvement projects and upgrades

Identify opportunities to improve system reliability, efficiency, and cost

Own and report Facility KPIs and drive for improvements

Own and improve facility procedures by drafting and revising facility SOPs and FORMs

Maintain accurate maintenance logs, records, and documentation

GMP HVAC and Environmental Control Systems

Provide engineering support and technical oversight for HVAC systems serving GMP manufacturing areas, controlled environments, laboratories, and hazardous materials handling areas.

Monitor and maintain critical environmental parameters, including differential pressure, temperature, airflow, and air-change rates.

Troubleshoot complex HVAC and building automation system issues, including air handling units, exhaust systems, controls, sensors, and instrumentation.

Investigate environmental excursions, pressure cascade deficiencies, ventilation failures, and other system deviations.

Support GMP and safety audits and facility inspection readiness

Support commissioning, qualification, requalification, and performance verification of critical facility systems.

Implement engineering improvements to enhance system reliability, environmental control, and operational efficiency.

Root Cause Investigations and Quality Management

Lead technical investigations involving facility equipment failures, environmental excursions, nonconformances, and other quality-related events.

Perform structured root cause analysis using methodologies such as 5 Whys, Fishbone diagrams, fault-tree analysis, and failure mode analysis.

Own and manage assigned nonconformance reports (NCRs), deviations, CAPAs, Change Controls, and related quality records from initiation through closure.

Develop comprehensive technical investigation reports supported by engineering data, system trends, maintenance history, and documented evidence.

Evaluate the effectiveness of implemented corrective actions and identify opportunities to prevent recurrence.

Collaborate with Quality Assurance to ensure investigations, impact assessments, and documentation comply with established quality management system requirements.

Maintain accountability for investigation timelines, quality event closure, and corrective action commitments.

Hazardous Materials and Laboratory Infrastructure

Our Mission

Synthego is a pioneering force in the biotechnology industry, dedicated to advancing the frontiers of CRISPR cell and gene therapies through cutting-edge CRISPR technology and expertise. Our mission is to provide unparalleled access to best-in-class CRISPR solutions at scale, empowering agility in life science research and development from discovery through clinical trials.

From streamlined approaches to licensing through full technical and regulatory support from our industry-leading experts, Synthego is enabling greater access to CRISPR technology driving to improved outcomes in patient therapeutic treatments.