Laboratory Technician - Vaccine Development

Responsibilities

• A successful candidate for this role must demonstrate adaptability in dynamic environments, effectively shifting priorities and approaches as project needs evolve, apply critical thinking to troubleshoot both scientific, mechanical and/or engineering challenges, and exercise sound judgment and confidence in making timely, data-informed decisions as well as willingness to step up into responsibilities outside of the job description.
• This role will support the development and optimization of vaccine candidates, working in a collaborative environment to advance products from research through regulatory approval, scale-up and regulated manufacturing of vaccine production.

Aseptic Technique & Laboratory Work

• Perform cell culture, bacterial culture, and molecular biology techniques under aseptic conditions.
• Prepare and maintain sterile media, buffers, and reagents.
• Conduct microbial and sterility testing to ensure contamination-free processes.

RNA and DNA Research & Development

• Extract, purify, and analyze RNA and DNA for vaccine applications.
• Develop and optimize nucleic acid-based formulations for vaccine candidates.

Vaccine Formulation & Manufacturing

• Assist in formulation development for nucleic acid vaccines.
• Support scale-up and process development for vaccine manufacturing.
• Characterize vaccine stability, potency, and immunogenicity utilizing validated assays or designing novel methods to assess.
• Laboratory Information Management Systems (LIMS) and Electronic Lab Notebook (ELN):
• Record, manage, and analyze experimental data using LIMS and ELN.
• Maintain accurate documentation of sample tracking, workflows, and quality control.
• Assist in integrating LIMS and ELN into laboratory workflows for data-driven decision-making.
• Ability to learn and adapt to new LIMS and ELN platforms as required.

Quality & Compliance

• Follow USDA-CVB approved manufacturing and laboratory quality procedures, Good Laboratory Practices, and biosafety guidelines in vaccine production.
• Maintain detailed laboratory records, protocols, and reports.
• Support regulatory documentation and technology transfer activities.

Requirements

• Technician who thrives in a dynamic environment, demonstrating flexibility, adaptability, and comfort navigating ambiguity while proactively solving problems and adjusting priorities as business needs evolve.
• This position is primarily responsible for RNA antigen manufacturing and downstream lipid nanoparticle encapsulation as well as testing associated with quality, sterility, reproducibility and safety.
• The successful candidate will have experience in aseptic techniques, working with RNA and DNA, vaccine formulation and manufacturing, and an understanding of Laboratory Information Management Systems (LIMS) or a willingness to learn.
• Bachelor’s or Master’s degree in Microbiology, Molecular Biology, Biochemistry, Biotechnology, Chemistry or a related field.
• 1-3 years of hands-on experience in aseptic technique, molecular biology, chemistry, and vaccine formulation or manufacturing.
• Experience with sterile handling of biological materials and working in BSL-2 environments.
• Knowledge of vaccine formulation principles, including adjuvants and stabilizers.
• Experience with or willingness to learn LIMS and ELN systems.
• Proven hands-on aptitude with the ability to work effectively with lab equipment and instrumentation, troubleshoot issues, and perform basic repairs or mechanical fixes as needed to support operations.
• Strong analytical and problem-solving abilities.
• Ability to work independently and as part of a multidisciplinary team.
• Excellent organizational skills and attention to detail.
• Strong written and verbal communication skills.
• Ability to quickly learn and adapt to new software systems, including LIMS and ELN

Preferred

• Experience with lipid nanoparticle (LNP) or viral vector vaccine formulation.
• Hands-on experience with downstream processing techniques such as ultrafiltration, chromatography, and lyophilization.
• Proficiency in RNA and DNA extraction, qPCR, and molecular cloning.
• Knowledge of immunological assays such as ELISA and flow cytometry.
• Prior experience in industry or a regulated laboratory environment.
• Experience leveraging tools for efficient data analysis or laboratory automation to streamline workflows.
• Familiarity with regulatory requirements for vaccine development.

Pay

$50,000-$60,000 Salary

Benefits

• Opportunity to participate in Equity Incentive Plan
• Insurance Package
• 401K
• 20 Days Annual PTO

Laboratory Technician - Vaccine Development

• Genvax Technologies · Ames, United States · Full-time · Posted 2026-10-22
• Salary: USD 50,000–60,000

Apply

[Apply at Genvax Technologies](https://apply.workable.com/genvax-technologies/j/0E31683A1C/apply)